Comparison between single loading–unloading indentation and continuous stiffness indentation

Estimation of local anisotropy of plexiform bone: Comparison between depth sensing micro-indentation and Reference Point Indentation.

The recently developed Reference Point Indentation (RPI) allows the measurements of bone properties at the tissue level in vivo. The goal of this study was to compare the local anisotropic behaviour of bovine plexiform bone measured with depth sensing micro-indentation tests and with RPI. Fifteen plexiform bone specimens were extracted from a bovine femur and polished down to 0.05µm alumina pas...

A simple indentation device for measuring micrometer-scale tissue stiffness.

Mechanical properties of cells and extracellular matrices are critical determinants of function in contexts including oncogenic transformation, neuronal synapse formation, hepatic fibrosis and stem cell differentiation. The size and heterogeneity of biological specimens and the importance of measuring their mechanical properties under conditions that resemble their environments in vivo present ...

Reliability of assisted indentation in measuring lumbar spinal stiffness.

The reliability of manual methods to assess spinal stiffness is modest at best. In response, instrumentation has been developed which may be reliable, but is often difficult to use in clinical settings. The purpose of this study was to determine the intra-rater reliability of assisted indentation (AI), a smaller, less automated technique of measuring spinal stiffness in vivo. Twenty-three asymp...

Scleral indentation without resection.

Review of Instrumented Indentation

Instrumented indentation, also known as depth-sensing indentation or nanoindentation, is increasingly being used to probe the mechanical response of materials from metals and ceramics to polymeric and biological materials. The additional levels of control, sensitivity, and data acquisition offered by instrumented indentation systems have resulted in numerous advances in materials science, parti...